Abstract Glioblastoma (GBM) stands as the most fatal brain tumor due to limited therapeutic options and high rates of drug resistance.Current surgical and pharmacological interventions usually fail to eradicate the aggressive GBM stem cells (GSCs), which leads to the deadly GBM occurrence.Although proteolysis-targeting chimeras (PROTACs) are prospe
One of the major goals in evolutionary developmental biology is to understand the relationship between gene Beds regulatory networks and the diverse morphologies and their functionalities.Are the diversities solely triggered by random events, or are they inevitable outcomes of an interplay between evolving gene networks and natural selection? Segme
Most children with asthma respond to low doses of inhaled corticosteroids, but a few remain symptomatic despite being prescribed the routine usual asthma medications.The first steps are to ensure that the diagnosis is correct and that the inhaled medications are being given regularly with an appropriately used device.If the children continue to be
In order to study the effects of irrigation with different levels of urban treated waste water on feeding value of forage sorghum (Var.Speed feed and Sugar graze), maize (Var.SC 704) and millet (Var.Nutrifeed) an experiment was conducted at Experimental Station Skin Care No.1, Astan Qods Razavi Mashhad, and Animal Nutrition Laboratory, College of A
Individuals with cerebral palsy (CP) have deficits in processing of somatosensory and proprioceptive information.To compensate for these deficits, they tend to rely on vision over proprioception in single plane upper and lower limb movements and in standing.It is not known whether this also applies to walking, an activity where the threat to balanc